Macaque SNV Database

a database for genetic divergence investigation among macaques

Last updated
Dec 30, 2019

Macaca SNV Database

MACSNVdb is an open-access SNV database comprising ~74.51 million high-quality non-redundant SNVs called from 20 macaques that may assist researchers to investigate interspecies genetic divergence between macaques. MACSNVdb allows users to browse and retrieve individual, sepcific and non-redundant SNVs. In particular, users can retrieve non-synonymous SNVs that may have deleterious effects on protein structure or function within macaque orthologs of human disease and drug-target genes. MACSNVdb also integrates gene functional annotation information including GO term, KEGG pathway, Pfam and InterPro domains.


  • MACSNVdb allows you to browse macaque individual SNVs, specific SNVs and non-redundant SNVs.
  • MACSNVdb also allows you to browse disease-associated and drug-targeted genes related SNVs, particularly non-synonymous SNVs which may have deleterious effects on protein structure or function.
  • The data collected from 20 macaques covered all the four species groups within genus Macaca, and thus, it can facilitate you to conduct genotyping comparative analysis between different macaques.
  • MACSNVdb not only provides detailed information for SNVs but also provides gene functional information.
  • MACSNVdb provides a flexible download function to assit you to search and retrieve desired SNVs


This work was supported by the National Natural Science Foundation of China (31501871 and 31530068), the Start-up Fund of Chengdu University (2081916062), the Key Research Fund on Sciences and Technologies for Joint Academic Institute and Local Enterprises of Sichuan (2018JZ0008), and partly funded by the Fundamental Research Funds for the Central Universities (2012017yjsy153).


Database developer Lianming Du ( and Zhenxin Fan (

Latest News more

Version 1.3
Updated reference genome to rheMac8 and annotation to Ensembl release 97.

Dec 30, 2019

Version 1.2
We used d3.js to reconstruct genotype comparative map to adapt to more individulas in the future.

Oct 14, 2018

Version 1.1
We changed the snp models in database for more efficient data retreving

Jul 16, 2018

Version 1.0
MACSNVdb 1.0 was released and is on line now

May 8, 2018


Individual SNVs193 129 390
Non-redundant SNVs74 506 801
Group-specific SNVs5 221 789
Species-specific SNVs6 766 099
SNVs in CDS486 697
Nonsynonymous SNVs209 064