Macaque SNV Database

Macaca SNV Database

MACSNVdb is an open-access SNV database comprising ~74.51 million high-quality non-redundant SNVs called from 20 macaques that may assist researchers to investigate interspecies genetic divergence between macaques. MACSNVdb allows users to browse and retrieve individual, sepcific and non-redundant SNVs. In particular, users can retrieve non-synonymous SNVs that may have deleterious effects on protein structure or function within macaque orthologs of human disease and drug-target genes. MACSNVdb also integrates gene functional annotation information including GO term, KEGG pathway, Pfam and InterPro domains.

Highlights

• MACSNVdb allows you to browse macaque individual SNVs, specific SNVs and non-redundant SNVs.
• MACSNVdb also allows you to browse disease-associated and drug-targeted genes related SNVs, particularly non-synonymous SNVs which may have deleterious effects on protein structure or function.
• The data collected from 20 macaques covered all the four species groups within genus Macaca, and thus, it can facilitate you to conduct genotyping comparative analysis between different macaques.
• MACSNVdb not only provides detailed information for SNVs but also provides gene functional information.
• MACSNVdb provides a flexible download function to assit you to search and retrieve desired SNVs

Acknowledgements

This work was supported by the National Natural Science Foundation of China (31501871 and 31530068), the Start-up Fund of Chengdu University (2081916062), the Key Research Fund on Sciences and Technologies for Joint Academic Institute and Local Enterprises of Sichuan (2018JZ0008), and partly funded by the Fundamental Research Funds for the Central Universities (2012017yjsy153).

Contact

Database developer Lianming Du (dulianming@cdu.edu.cn) and Zhenxin Fan (zxfan@cdu.edu.cn)