Macaque SNP Database

a database for genetic divergence investigation among macaques

Version
1.2
Last updated
Oct 14, 2018

Macaca SNP Database

MACSNPdb is an open-access SNP database comprising ~80.88 million high-quality non-redundant SNPs called from 20 macaques that may assist researchers to investigate interspecies genetic divergence between macaques. MACSNPdb allows users to browse and retrieve individual, sepcific and non-redundant SNPs. In particular, users can retrieve non-synonymous SNPs that may have deleterious effects on protein structure or function within macaque orthologs of human disease and drug-target genes. MACSNPdb also integrates gene functional annotation information including GO term, KEGG pathway, Pfam and InterPro domains.

Highlights

  • MACSNPdb allows you to browse macaque individual SNPs, specific SNPs and non-redundant SNPs.
  • MACSNPdb also allows you to browse disease-associated and drug-targeted genes related SNPs, particularly non-synonymous SNPs which may have deleterious effects on protein structure or function.
  • The data collected from 20 macaques covered all the four species groups within genus Macaca, and thus, it can facilitate you to conduct genotyping comparative analysis between different macaques.
  • MACSNPdb not only provides detailed information for SNPs but also provides gene functional information.
  • MACSNPdb provides a flexible download function to assit you to search and retrieve desired SNPs

Acknowledgements

This work was supported by the National Natural Science Foundation of China (31501871 and 31530068), the Start-up Fund of Chengdu University (2081916062), the Key Research Fund on Sciences and Technologies for Joint Academic Institute and Local Enterprises of Sichuan (2018JZ0008), and partly funded by the Fundamental Research Funds for the Central Universities (2012017yjsy153).

Contact

Database developer Lianming Du (dulianming@cdu.edu.cn) and Zhenxin Fan (zxfan@cdu.edu.cn)

Latest News

Version 1.2
We used d3.js to reconstruct genotype comparative map to adapt to more individulas in the future.

Oct 14, 2018

Version 1.1
We changed the snp models in database for more efficient data retreving

Jul 16, 2018

Version 1.0
MACSNPdb 1.0 was released and is on line now

May 8, 2018

Statistics

Individuals20
Groups5
Species10
Individual SNPs215 932 420
Non-redundant SNPs80 879 499
Group-specific SNPs5 079 706
Species-specific SNPs7 252 490
SNPs in CDS522 465
Nonsynonymous SNPs220 098